Bone remodeling in beta thalassemia patients, does it differ between Thalassemia major and intermedia?

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چکیده

منابع مشابه

Bone mineral density in beta-thalassemia major and intermedia.

OBJECTIVE This study was conducted to assess bone mineral density (BMD) and bone mineral content (BMC) in patients with thalassemia major and intermedia, and to correlate them with biochemical and hematological profile. DESIGN 106 thalassemic patients (49 major and 57 intermedia) were scanned by dual energy xray absorptiometry technique for BMD and BMC at lumbar spine and femoral neck. The ef...

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Malignancies in patients with beta-thalassemia major and beta-thalassemia intermedia: a multicenter study in Iran.

BACKGROUND Beta thalassemia is one of the most common genetic disorders in the world. The aim of this study was to determine the frequency, characteristics, and pattern of malignancies in patients with beta thalassemia major (BTM) and beta thalassemia intermedia (BTI) in Iran. METHODS We conducted a multicenter study via a retrospective chart review of patients with BTM and BTI between 2002 a...

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Side effects of hydroxyurea in patients with Thalassemia major and thalassemia intermedia and sickle cell anemia

Background Sickle hemoglobin is the most common abnormal hemoglobin in the United States. Hemoglobin S arises as a result of a single amino acid substitution (glutamic acid to valin at position 6 of the β-globine chain). The presence of fetal hemoglobin (HbF) plays a relatively protective role since a significant amount of HbF interferes with HbS polymerization, the pathogenesis mechanism of ...

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Endocrine Disorders in Beta thalassemia Major Patients

Background Thalassemia is the most common hereditary disorder worldwide. The patient's’ survival is dependent on lifetime blood transfusion which leads to iron overload and its toxicity on various organs including endocrine glands. The study aimed to investigate endocrine disorders in patients with Beta-thalassemia major in the Southern Khorasan province, Iran. Materials and Methods In this des...

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Prevalence of HCVAb and HBsAg in Patients with Beta-thalassemia Major in Amirkola Thalassemia Center

Background and purpose: Beta-thalassemia major is a genetic disorder with known globin defect that leads to chronic hemolytic anemia. Due to the need for recurrent blood transfusion, the risk of infectious diseases such as hepatitis is higher in these patients. Materials and methods: This cross-sectional study recruited 518 patients with thalassemia major in Amirkola Thalassemia Center, 2013-2...

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ژورنال

عنوان ژورنال: QJM: An International Journal of Medicine

سال: 2018

ISSN: 1460-2725,1460-2393

DOI: 10.1093/qjmed/hcy200.130